MDM2 Polyclonal Antibody
简要描述:MDM2 Polyclonal Antibody宿主: Polyclonal, Rabbit,IgG反应性: Human;Rat;Mouse;应用: IF;WB;IHC;ELISA
产品型号: YP-Ab-00569
所属分类:多克隆抗体
更新时间:2024-10-31
详细说明:
MDM2 Polyclonal Antibody
抗体,也叫免疫球蛋白(Ig),是一种能特异性结合抗原的糖蛋白,而抗原是在易感染动物体内引发抗体产生的物质。在体内,抗体是由于外源性分子的侵袭而产生的。抗体以一个或者多个Y字形单体存在,每个Y字形单体由4条多肽链组成,包含两条相同的重链和两条相同的轻链。轻链和重链是根据它们的分子量大小来命名的。Y字形结构的顶端是可变区,为抗原结合部位。任何一个抗体的轻链都可以分为κ或λ型(基于小分子多肽结构上的差异),每一个抗体的重链则决定了它的类或型。
产品详情
MDM2 Polyclonal Antibody detects endogenous levels of MDM2 protein.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from the C-terminal region of human MDM2. AA range:381-430
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
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备注:图片仅供参考。仅供科研,不可用于临床。